c. 1025★★★★★
Ibn Sina (Avicenna) completes The Canon of Medicine, a medical encyclopedia used as a standard text in the Islamic world and Europe for centuries.
Science· Iran
969★★★★★
The Shia Fatimid Caliphate takes Egypt and builds Cairo as its new capital, along with the al-Azhar mosque.
WarPoliticsReligion· Egypt
July 16, 1054★★★★★
Papal legates lay a bull of excommunication on the altar of Hagia Sophia, marking the split between Roman Catholic and Eastern Orthodox churches.
Religion· Turkey, Italy
August 26, 1071★★★★★
The Seljuks defeat and capture Byzantine Emperor Romanos IV, opening Anatolia to Turkish settlement.
War· Turkey
July 15, 1099★★★★★
The First Crusade takes Jerusalem after a siege, followed by a massacre of its inhabitants.
WarReligion· Israel, Palestine
1147 – 1149★★★★★
Launched after the fall of Edessa and led by Louis VII of France and Conrad III of Germany, the crusade ends in failure before Damascus.
WarReligion· Syria, Turkey, France, Germany