Joan of Arc burned at Rouen
Captured and tried by a pro-English church court, Joan of Arc is burned at the stake; she was rehabilitated in 1456 and canonized in 1920.
Captured and tried by a pro-English church court, Joan of Arc is burned at the stake; she was rehabilitated in 1456 and canonized in 1920.
Returning from exile, the banker Cosimo de' Medici becomes the de facto ruler of Florence; the Medici become major patrons of Renaissance art.
Filippo Brunelleschi's dome for Florence Cathedral is completed, an emblematic engineering feat of the Renaissance.
Johannes Gutenberg develops metal movable-type printing in Mainz, launching Europe's printing revolution.
Ottoman forces under Sultan Mehmed II capture Constantinople, ending the Byzantine Empire.
The marriage of Ferdinand of Aragon and Isabella of Castile later unites their crowns, laying the foundation of a unified Spain.
Ivan III of Moscow faces down the Great Horde, which withdraws; traditionally seen as the end of Tatar overlordship in Russia.
Henry Tudor defeats and kills Richard III, taking the throne as Henry VII and founding the Tudor dynasty, effectively ending the Wars of the Roses.
The Portuguese navigator Bartolomeu Dias became the first European to sail around the southern tip of Africa, proving the Indian Ocean could be reached by sea.
Emir Muhammad XII surrenders to Ferdinand and Isabella, ending the last Muslim state on the Iberian Peninsula.
Ferdinand and Isabella order the Jews of Castile and Aragon to convert or leave their kingdoms.
Lorenzo "the Magnificent", ruler of Florence and patron of artists such as Botticelli and Michelangelo, dies.
Spain and Portugal agree to divide newly found lands outside Europe along a meridian in the Atlantic.
Vasco da Gama's fleet left Lisbon, rounded the Cape of Good Hope, sailed up the East African coast and reached Calicut, opening a direct sea route between Europe and Asia.
From the 16th to the 19th century, an estimated 12.5 million enslaved Africans were shipped across the Atlantic to the Americas, with profound consequences for both continents.
A Portuguese fleet under Pedro Álvares Cabral reaches the coast of Brazil, beginning Portugal's claim to and colonization of the land.
Leonardo da Vinci begins painting the Mona Lisa in Florence, which later becomes the world's most famous painting.
Michelangelo paints the frescoes of the Sistine Chapel ceiling in the Vatican, including The Creation of Adam.
Martin Luther publishes his Ninety-five Theses against indulgences, sparking the Protestant Reformation.
Suleiman I rules the Ottoman Empire at the height of its territorial, legal and cultural power.
The English Parliament passes the Act of Supremacy, declaring Henry VIII Supreme Head of the Church of England and breaking with papal authority.
Nicolaus Copernicus's On the Revolutions of the Heavenly Spheres is printed, placing the Sun at the centre and launching the Scientific Revolution.
Andreas Vesalius publishes his illustrated work on human anatomy based on direct dissection, founding modern anatomy.
An ecumenical council of the Catholic Church meets at Trent, reaffirming Catholic doctrine and launching the Counter-Reformation in response to Protestantism.
Ivan IV (Ivan the Terrible) is crowned in Moscow with the title of Tsar, marking the beginning of the Tsardom of Russia.
William Shakespeare, the most celebrated playwright and poet in the English language, is born in Stratford-upon-Avon.
The Dutch provinces revolt against Spanish rule; the war ends with Spain recognising the independence of the Dutch Republic.
The Kingdom of Poland and the Grand Duchy of Lithuania unite into a single federal state with a shared monarch and parliament.
The fleet of the Holy League, formed by Spain, Venice and the Papacy, defeats the Ottoman navy in the Gulf of Patras.
Thousands of Huguenot Protestants are killed in Paris and other French cities during the French Wars of Religion.
The Gregorian calendar takes effect in Catholic countries: Julian 4 October 1582 is followed by 15 October.
The Armada sent by Philip II to invade England is defeated by the English navy at the Battle of Gravelines and scattered during its retreat.
King Henry IV issues an edict granting substantial religious rights to the Huguenots, ending the French Wars of Religion.
Queen Elizabeth I grants a royal charter to the East India Company, which later comes to rule much of the Indian subcontinent.
Miguel de Cervantes publishes the first part of Don Quixote, often regarded as one of the first modern novels.
Johannes Kepler publishes Astronomia nova, stating his first two laws of planetary motion, including elliptical orbits.
Observing with his own telescope, Galileo Galilei discovers the moons of Jupiter, publishing them in Sidereus Nuncius in 1610 in support of heliocentrism.
An assembly of the land elects Michael Romanov as Tsar, ending the Time of Troubles; the Romanovs rule Russia until 1917.
Shakespeare dies in Stratford-upon-Avon, leaving some 39 plays and 154 sonnets.
Beginning with a revolt in Bohemia, the conflict spreads across Central Europe, drawing in the major European powers and causing enormous loss of life.
William Harvey publishes De Motu Cordis, demonstrating that the heart pumps blood in a continuous circuit around the body.
A series of conflicts between the Royalists of Charles I and the Parliamentarians, ending in victory for Parliament under Oliver Cromwell.
Galileo dies at Arcetri near Florence, where he had been under house arrest since his trial by the Inquisition in 1633.
Isaac Newton, founder of classical mechanics and co-inventor of calculus, is born at Woolsthorpe, England.
The treaties of Westphalia end the Thirty Years' War and lay foundations for the modern concept of state sovereignty.
Convicted of high treason, King Charles I is beheaded at Whitehall, London, and England becomes a republic.
Jesuit missionary Alexandre de Rhodes publishes in Rome a Vietnamese–Portuguese–Latin dictionary, a milestone in the development of the Latin-based Vietnamese alphabet.
The monarchy is restored in England, Scotland and Ireland as Charles II returns to London to take the throne.
A fire starting in a bakery on Pudding Lane destroys much of the medieval City of London, including Old St Paul's Cathedral.
Using microscopes of his own making, Antonie van Leeuwenhoek describes single-celled organisms in water and reports them to the Royal Society.