541★★★★★
Plague of Justinian
The first recorded pandemic of bubonic plague sweeps the Mediterranean, devastating the Byzantine Empire and killing vast numbers.
Disease· Turkey, Egypt
The first recorded pandemic of bubonic plague sweeps the Mediterranean, devastating the Byzantine Empire and killing vast numbers.
Teotihuacan in the Valley of Mexico grows into one of the largest cities in the world of its time, with the Pyramid of the Sun and the Avenue of the Dead.
Maya city-states such as Tikal, Palenque and Calakmul reach their height in architecture, writing, astronomy and calendrics.
The Soninke Ghana Empire (Wagadu) flourished in what is now Mauritania and Mali, growing rich from control of the trans-Saharan gold and salt trade.