1676★★★★★
Leeuwenhoek observes microorganisms
Using microscopes of his own making, Antonie van Leeuwenhoek describes single-celled organisms in water and reports them to the Royal Society.
Science· Netherlands
Using microscopes of his own making, Antonie van Leeuwenhoek describes single-celled organisms in water and reports them to the Royal Society.
King Ramathibodi I founds the capital of Ayutthaya, beginning a Siamese kingdom that lasts over four centuries.
From the 16th to the 19th century, an estimated 12.5 million enslaved Africans were shipped across the Atlantic to the Americas, with profound consequences for both continents.
Ismail I proclaims himself shah in Tabriz, founding the Safavid dynasty and making Twelver Shia Islam Iran's state religion.
The shogunate expels the Portuguese and severely restricts foreign contact, allowing only Dutch and Chinese trade at Nagasaki.