Copernicus publishes heliocentric theory
Nicolaus Copernicus's On the Revolutions of the Heavenly Spheres is printed, placing the Sun at the centre and launching the Scientific Revolution.
Nicolaus Copernicus's On the Revolutions of the Heavenly Spheres is printed, placing the Sun at the centre and launching the Scientific Revolution.
Andreas Vesalius publishes his illustrated work on human anatomy based on direct dissection, founding modern anatomy.
King Ramathibodi I founds the capital of Ayutthaya, beginning a Siamese kingdom that lasts over four centuries.
From the 16th to the 19th century, an estimated 12.5 million enslaved Africans were shipped across the Atlantic to the Americas, with profound consequences for both continents.
Ismail I proclaims himself shah in Tabriz, founding the Safavid dynasty and making Twelver Shia Islam Iran's state religion.
Suleiman I rules the Ottoman Empire at the height of its territorial, legal and cultural power.
Lê loyalists led by Nguyễn Kim enthrone Lê Trang Tông, beginning a long civil war between the restored Lê and the Mạc.